Linear reconstruction of absorption perturbations in coherent ultrasound-modulated optical tomography.

Discrete form sensitivity functions are derived for a number of measurement types employed in autocorrelation-based ultrasound-modulated optical tomography. The Jacobian for a particular problem is constructed from the set of such sensitivity functions arising from a raster scan of a focused ultrasound field through a turbid medium. A linear reconstruction of an absorption perturbation is performed in a simulated difference data experiment, and the performance of the measurement types is compared under different degrees of added noise.